Goku would win. Him blasting Kid Buu off the face of the universe helped solidify that he is really one of the best fighters in the universe. I don't give a fuck what anyone says. He defeated a psychotic little pink bastard that has destroyed solar systems(destroying fucking Earth and all of humanity too) and is literally pure evil and whose only thought is to kill. That's pretty badass.
"At the end of the day, I don’t give a crap who’s taking what. The steroids are not going to help them when I hit them. Take as much as you like, I don’t care." - Mark Hunt